FIRSTVAL

01Health & Life Sciences

Evidence in, outcomes out.

From molecule to member: a value engine that models trial economics, care pathways, patient access and commercial performance as one connected system — under GxP, HIPAA and EU AI Act discipline.

North Star

Cost per validated patient outcome

The value engine, end to end

Discover → Model → Twin → Agents → Govern → Compound

The same six moves we run everywhere, expressed in the physics of this industry.

01

Discover

Where does clinical and commercial value actually pool?

Value pool map by therapy area

02

Model

What causes cycle time, adherence and access to move?

Causal model of trial + pathway

03

Twin

What happens if we change site mix or protocol?

Trial + care pathway twin

04

Agents

Who executes the change every day?

Multi-agent operating layer

05

Govern

Is it validated, auditable and safe?

GxP + EU AI Act control file

06

Compound

Does the gain hold next quarter?

Outcome contract + drift monitor

Where the value is

Value pools and their drivers

Before a twin is built, we agree where the money sits and what moves it.

Value pool

Clinical development

Driver

Trial cycle time and site productivity

Measured as

Days saved × cost of delay

Value pool

Patient access

Driver

Time to therapy, prior-auth throughput

Measured as

Scripts converted per 1,000 referrals

Value pool

Care delivery

Driver

Length of stay, readmission, no-shows

Measured as

Bed-days and avoidable episodes

Value pool

Commercial

Driver

Field effort allocation, HCP engagement quality

Measured as

Revenue per rep-hour

Use cases

Where value is already sitting in Health & Life Sciences

Each one is a number somebody already owns, a twin that models it, and an agent that moves it inside a defined authority. Filter by function.

14 use cases

Referral and intake automation

Reads referral letters, faxes and scans, extracts the clinical detail, and books the patient into the right pathway without a queue in between.

Moves
Referral-to-appointment days
Twin
Process Twin
Capability
Document AI + OCR

Hospital capacity and census simulation

Forecasts census, length of stay and discharge timing so staffing and beds are planned against next week rather than last week.

Moves
Bed-days per episode
Twin
Process Twin
Capability
Simulation + forecasting

Readmission risk and intervention

Identifies who is likely to return and what to change while the patient is still in the building, where intervention is cheapest.

Moves
Avoidable readmissions
Twin
Care Pathway Twin
Capability
Risk stratification

Hospital-acquired infection monitoring

Watches the pattern across wards, staff movement and procedures, and raises the signal early enough to break the chain.

Moves
Infection rate per 1,000 bed-days
Twin
Care Pathway Twin
Capability
Anomaly detection

Imaging triage support

Prioritises studies most likely to contain an urgent finding so the radiology queue is ordered by risk, not by arrival time. Support, never a substitute for the clinician.

Moves
Time to urgent report
Twin
Care Pathway Twin
Capability
Vision models

Clinical decision support with citations

Surfaces guideline-grounded options at the point of decision, every recommendation carrying the source paragraph behind it.

Moves
Guideline adherence rate
Twin
Care Pathway Twin
Capability
Cited RAG

Medical claims fraud, waste and abuse

Detects overpayment and abusive billing patterns across providers and members without freezing legitimate claims in the process.

Moves
Overpayment avoided per dollar reviewed
Twin
Financial Crime Twin
Capability
Pattern detection

Plan pricing and utilisation forecasting

Prices plans against forecast utilisation and cohort risk rather than last year's book, so margin does not depend on the renewal cycle guessing well.

Moves
Medical loss ratio accuracy
Twin
Financial Twin
Capability
Forecasting

Self-pay and remittance recovery

Predicts which balances are collectible and which route collects them, and drafts the patient communication that works.

Moves
Net collection rate
Twin
Financial Twin
Capability
Predictive + generation

Trial site selection and recruitment

Ranks sites on realistic enrolment rather than reputation, and rebalances recruitment while the curve can still be changed.

Moves
Cost of enrolment delay avoided
Twin
Clinical Trial Twin
Capability
Predictive ranking

Adverse event signal detection

Reads case reports, literature and public channels for emerging safety signals and routes them into the regulated workflow with the evidence intact.

Moves
Time to signal confirmation
Twin
Compliance Twin
Capability
NLP + classification

Therapy effectiveness from real-world text

Mines patient and clinician text for effectiveness and tolerability patterns that structured data alone does not carry.

Moves
Evidence generated per study dollar
Twin
Clinical Trial Twin
Capability
NLP at scale

Field effort and prescriber targeting

Allocates field and medical effort to the accounts where engagement changes behaviour, inside compliant content boundaries.

Moves
Revenue per rep-hour
Twin
Commercial Twin
Capability
Next-best-action

Population and outbreak forecasting

Forecasts encounter volumes for seasonal and emergent conditions so capacity, staffing and supply are positioned ahead of the wave.

Moves
Surge coverage rate
Twin
Process Twin
Capability
Epidemiological forecasting

Outcome twins

Twins, levers, features and the agents that run them

Each twin owns a set of levers. Each feature moves one lever. Each agent executes inside a defined authority.

Clinical Trial Twin

Simulate protocol, site mix and enrolment before a single patient is screened.

Levers

Screen-fail rateSite activation timeProtocol amendmentsQuery resolution

Features

  • Enrolment forecasting
  • Site scorecards
  • Protocol stress test
  • Deviation triage

Multi-agent layer

  • Enrolment Agent

    Rebalances recruitment across sites weekly.

  • Data Query Agent

    Drafts and resolves EDC queries with audit trail.

Care Pathway Twin

Model the patient journey end to end and find where outcomes and dollars leak.

Levers

Length of stayReadmissionNo-show rateCare gap closure

Features

  • Pathway simulation
  • Capacity planning
  • Risk stratification
  • Discharge orchestration

Multi-agent layer

  • Scheduling Agent

    Fills capacity and pre-empts no-shows.

  • Care Gap Agent

    Closes overdue interventions with clinician approval.

Access & Reimbursement Twin

Turn prior authorization and payer friction into a measured throughput system.

Levers

Prior-auth turnaroundDenial rateTime to therapy

Features

  • Denial prediction
  • Evidence packaging
  • Payer policy retrieval

Multi-agent layer

  • Prior-Auth Agent

    Assembles and submits payer-ready evidence bundles.

Commercial Twin

Allocate field and medical effort to the accounts that move outcomes.

Levers

Rep effort mixHCP engagement qualitySample and spend efficiency

Features

  • Next-best-action
  • Territory rebalancing
  • Compliant content generation

Multi-agent layer

  • Field Planning Agent

    Re-plans territory effort against outcome value.

Unit economics

ROI calculator — per feature, per unit

Set your volume, switch features on or off, and move each impact to your own evidence. Everything is expressed per patient episode.

Episodes per year

120,000

Contribution per patient episode

$800

Episode economics; substitute trial patients or scripts as the unit where relevant.

Annual program investment

$3.5m

Clinical Trial Twin

Unit costCost of delay avoided

4.0% — Reallocates recruitment before the enrolment curve flattens.

$16.3m

annual value

Care Pathway Twin

Unit costLength of stay

3.5% — Removes waiting time between clinical decision and discharge.

$14.3m

annual value

Care Pathway Twin

VolumeUtilised capacity

3.0% — Fills slots that would otherwise be lost the same day.

$2.9m

annual value

Access Twin

LeakageDenials and abandonment

25.0% — Reduces value lost between prescription and therapy start.

$13.9m

annual value

Commercial Twin

Unit revenueRevenue per episode

1.5% — Better mix and adherence on the same volume.

$7.6m

annual value

Value by feature

Annual value contributed by each active feature at current settings.

Value and ROI vs volume

How engineered value and ROI move as episodes per year change. The marker is your current setting.

Cumulative value vs investment

Where the curve crosses the investment line is payback.

Value mix by lever

Which lever the engineered value is actually coming from.

Baseline contribution

$96.0m

Engineered annual value

$54.9m

ROI on program

1469%

Payback

0.8 months

Directional model. In an engagement every number here is replaced by your measured baseline, signed off by finance, and written into the outcome contract before any agent goes live.

Scale

How this compounds from one unit to the enterprise

01

One site / one service line

Prove the causal model on a bounded population with a validated baseline.

02

One therapy area / one region

Reuse the twin, swap the data contracts, keep the control file.

03

Enterprise

Shared agent runtime, per-market guardrails, one accepted number.

Integrations

Domain platforms we connect

Vendor-agnostic by design. Connectors are added per engagement — no platform lock-in.

Clinical

  • Epic
  • Cerner
  • Veeva Vault
  • Medidata Rave
  • OpenClinica

Commercial

  • Veeva CRM
  • Salesforce Health Cloud
  • IQVIA
  • Komodo

Data & cloud

  • Snowflake
  • Databricks
  • Azure Health Data Services
  • FHIR servers

AI

  • Azure OpenAI
  • Anthropic
  • Vertex AI
  • domain SLMs

Regulations and standards

What we are held to in this industry

Compliance is a design input, not a review gate. Every agent action is logged, attributable and reversible.

HIPAA

PHI handling, minimum necessary, BAAs across every agent hop.

GDPR

Lawful basis, special-category data, DPIA per automated decision.

EU AI Act

High-risk classification for clinical decision support; logging and human oversight.

GxP / 21 CFR Part 11

Validated systems, e-signatures, immutable audit trail.

MDR / IVDR

Boundary control so no agent becomes an unregistered medical device.

Standards supported

HL7 FHIRSNOMED CTICD-10CDISC SDTM/ADaMISO 27001ISO 13485NIST AI RMFSOC 2 Type II

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